This white paper explores the fundamental design challenges faced when creating and producing high-frequency modules for a range of wireless system applications, and the tools required for an effective workflow supporting the design and integration of these modules in the shortest time possible. Much of this capability can be addressed using the Cadence® AWR Design Environment® platform to define and manage the electrical and physical attributes of a wireless module and to perform circuit, system, and electromagnetic (EM) co-simulation within a single integrated environment that also supports interoperability with industry-leading CAD layout tools.